Meta-analysis of feasibility of ovarian preservation in early youth endometrial cancers

VernacularTitle:年轻早期子宫内膜癌保留卵巢的可行性Meta分析
Author: Haibin LIU
Publication Type:Journal Article
Keywords: Endometrial neoplasms/surgery; Ovary/surgery; Meta-analysis
From: Journal of Chinese Physician 2014;16(8):1068-1070,1075
CountryChina
Language:Chinese
Abstract: Objective To investigate feasibility of ovarian preservation in early youth endometrial cancer (EC).Methods We searched the database.All the calculations and statistical tests were performed with the Revman 5.2 software.The odds risk (OR) of cancer recurrence or death was taken as observation index.Results The experimental group was compared to control group,the risks of relapse and death were similar.The combined OR of all relapse risk was 0.87 with a 95％ of confidence interval (0.44 ～ 1.70).While the combined OR of all death risk was 0.70 with a 95％ of confidence interval (0.42 ～ 1.15).Conclusions The present data show that ovarian preservation in early youth EC is feasible because the treatment can not increase the risks of relapse and death.However,this conclusion needs to be further confirmed with high-quality randomized clinical trials.