Evaluation of early alterations of common carotid artery structure and function in patients with hypertriglyceridemia using ultrasound radio-frequency analyzing technique
10.3760/cma.j.issn.1673-4181.2014.04.009
- VernacularTitle:应用超声射频信号技术软件评估高甘油三脂患者颈动脉结构和功能的早期改变
- Author:
Jun ZHANG
;
Xinmin ZHAO
;
Yanhua ZHOU
;
Lei ZHOU
;
Lin SHI
- Publication Type:Journal Article
- Keywords:
Ultrasound;
Hypertriglyceridemia;
Carotid arteries;
Early stage
- From:
International Journal of Biomedical Engineering
2014;37(4):227-229,250,后插4
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical value of early alterations of carotid arterial intima-media thickness (IMT) and elastic function in patients with hypertriglyceridemia (HTG) using ultrasound radio-frequency technique.Methods 48 patients (triglyceride value ≥ 1.8 mmol/L) were chosen as HTG group.Quantitative intimamedia thickness (QIMT) and quantitative arterial stiffness (QAS) techniques were used to observe the alterations of carotid arterial IMT and elastic index,including diameter of carotid artery (D),distensibility coefficient (DC),compliance coefficient (CC),elasticity coefficient (α),elasticity coefficient (β) and pulse wave velocity (PWV).50 healthy subjects were recruited in control group.Differences of the above-mentioned parameters were analyzed,as well as the elastic index connections between the two groups.Results IMT,α,β,and PWV index of bilateral carotid arteries in HTG group was higher than that of the control group,while the DC and CC index was lower,and the differences was statistically significant (P＜0.05).Within the groups there were differences between the elastic indexes of bilateral carotid arteries.In control group and the HTG group:CCL＞CCR,αL＞αR,βL＞βR,PWVL＞PWVR.CC was negatively correlated to α,β and PWV (P＜0.05).Meanwhile,there was positive correlation among α,β and PWV (P＜0.05).The differences of D between two groups had no statistical significance (P＞0.05).Conclusions The abnormity of arterial occurs earlier than the morphological change,while the ultrasound radio-frequency technique can provide information of earlier alteration of common carotid arteries structure and elastic function in patients with HTG,which is a significant method of testing early alteration of carotid elastic in patients with HTG.
