Distribution and drug resistance of clinically isolated Pseudomonas aeruginosa
10.3969/j.issn.1673-4130.2014.16.009
- VernacularTitle:临床分离铜绿假单胞菌分布及耐药性分析
- Author:
Lili FANG
;
Xiuyu SONG
;
Xiaobo MA
;
Yanqing ZHENG
;
Bo ZHU
;
Gangsen ZHENG
- Publication Type:Journal Article
- Keywords:
Pseudomonas aeruginosa;
drug resistance,microbial;
pathogenic bacterium
- From:
International Journal of Laboratory Medicine
2014;(16):2142-2143,2146
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical distribution and the drug resistance characteristics of Pseudomonas aeruginosa . Methods The results of the bacterial culture and the antimicrobial susceptibility test in the hospital from July 2007 to October 2008 were performed the retrospective analysis.Results Totally 335 strains of Pseudomonas aeruginosa were isolated,accounting for 9.2% of isolated pathogenic bacteria.The main specimen source was sputum,accounting for 77.6%.The ICU ward was the high incidence area.The resistance rates of Pseudomonas aeruginosa to amikacin,piperacillin/tazobactam,tobramycin,levofloxacin, cefepime,gentamicin,ticarcillin and ciprofloxacin were less than 10%.The resistance rates of imipenem-insensitive Pseudomonas aeruginosa to aztreonam,ceftazidime,ciprofloxacin,levofloxacin,piperacillin/tazobzctam were significantly higher than those in imi-penem-sensitive Pseudomonas aeruginosa (P <0.05).Conclusion The multiple drug resistance phenomena of Pseudomonas aerugi-nosa generally exist,amikacin,piperacillin/tazobactam and tobramycin are recommended for the treatment of infections caused by Pseudomonas aeruginosa .
