Earlier diagnostic value of Ischemia modified albumin in acute coronary syndrome patients
10.3969/j.issn.1673-4130.2014.16.022
- VernacularTitle:缺血修饰清蛋白在急性冠状动脉综合征早期诊断中的价值
- Author:
Ranrong ZHANG
;
Zheng LIU
;
Zhenfan YANG
;
Guangbin QIU
- Publication Type:Journal Article
- Keywords:
ischemia modified albumin;
acute coronary syndrome;
unstable angina;
acute myocardial infarction
- From:
International Journal of Laboratory Medicine
2014;(16):2174-2175,2178
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore earlier diagnostic value of ischemia modified albumin(IMA)in acute coronary syndrome(ACS) patients.Methods We detected serum IMA and CK-MB in 117 patients with ACS and 100 healthy controls to analyze the diagnos-tic value of IMA in ACS.Results When the critical value of 73.25 U/mL,serum IMA testing determine the ACS of the sensitivity, specific,positive predictive value and negative predictive value of 89.6%,86.0%,84.93% and 86.0% respectively.IMA levels in serum in patients with AMI group was obviously higher than that of healthy control group(P <0.05).Sensitivity could be improved to 91.5% when detected IMA and CK-MB together.And the specific was 71.5%.Conclusion Serum IMA can be used as sensitive index of early diagnosis and risk stratification of ACS.Detecting IMA and CK-MB can improve the diagnostic sensitivity of ACS.
