Three kinds of noninvasive screening application in diagnosis of early prostate cancer
10.3969/j.issn.1671-8348.2014.22.013
- VernacularTitle:3种无创检查在前列腺癌初筛诊断中的应用价值
- Author:
Shu CAO
;
Weilie HU
;
Lixin HAN
;
Huixia CAO
- Publication Type:Journal Article
- Keywords:
prostate cancer;
MRI;
transrectal uhrasonography;
direct rectal examination
- From:
Chongqing Medicine
2014;(22):2868-2869,2872
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of noninvasive diagnosis methods direct rectal examination (DRE) ,transrectal ultra-sonography(TRUS) and multiparametric magnetic resonance imaging(MP-MRI) for prostate cancer detection .Methods The clini-cal data of 113 patients suspected prostatic cancer were analyzed retrospectively .Every patient was examined by TRUS ,DRE and MP-MRI before pathology or operation .The sensitivity rate and the specificity rate of DRE ,TRUS and MP-MRI were calculated and compared among the three methods .Results The sensitivity rate and the specificity rate of prostate cancer were 33 .3% and 88 .7% for DRE ,62 .7% and 67 .7% for TRUS ,86 .3% and 83 .9% for MP-MRI respectively ,two comparison between the three group had statisfically difference(P<0 .05) .But ,of prostate cancer with prostate specific antigen (PSA) 4 .0~10 .0 ng/mL in gray zone ,the sensitivity rate and the specificity rate were 27 .8% and 86 .5% for DRE ,44 .4% and 59 .5% for TRUS ,77 .8% and 81 .1% for MP-MRI ,two comparison between the three group had statisfically difference(P<0 .05) .Conclusion MP-MRI has bet-ter detection efficiency .It could obviously reduce the missed diagnosis rate on PCA with PSA in gray zone .
