Application value of homocysteine detection in diagnosing acute myocardial infarction
10.3969/j.issn.1673-4130.2014.15.017
- VernacularTitle:同型半胱氨酸的检测对诊断急性心肌梗死的应用价值
- Author:
Wei HU
;
Anhui SHI
;
Jiang CHEN
;
Xiaobin HU
- Publication Type:Journal Article
- Keywords:
acute myocardial infarction;
unstable angina;
cysteine;
creatine kinase isoenzyme
- From:
International Journal of Laboratory Medicine
2014;(15):2006-2007,2010
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical application value of serum homocysteine(Hcy) detection in diagnosing acute myo-cardial infarction .Methods 78 cases of acute myocardial infarction in the hospital from January to December 2013 were selected as the acute myocardial infarction group ,69 cases of unstable angina as the unstable angina group and contemporaneous 78 healthy per-sons undergoing the physical examination as the control group .The serum Hcy ,myoglobin and creatine kinase isoenzyme were de-tected and the detection results were performed the statistical analysis .Results The serum Hcy levels and the positive rate in the a-cute myocardial infarction group were significantly higher than those in the unstable angina group (P<0 .05) ,but serum myoglobin and creatine kinase isoenzyme had no statistical differences in the concentration and positive rate between these two groups (P>0 .05) .The serum Hcy concentration and the positive rate in the acute myocardial infarction group and the unstable angina group were higher than those in the control group(P<0 .05) .The ROC curve analysis showed that the efficiency for diagnosing acute my-ocardial infarction from high to low in turn was MYO ,Hcy and CK-MB .Conclusion Serum Hcy may be used as a routine index for diagnosing acute myocardial infarction ,which has certain clinical value for the condition monitoring and prognosis of the disease ,and also has certain clinical significance for the differential diagnosis between acute myocardial infarction and unstable angina .
