Progress of lactobacillus casei cell wall extract-induced mouse model of Kawasaki disease
10.3760/cma.j.issn.1673-4408.2014.05.019
- VernacularTitle:干酪乳杆菌细胞壁萃取物诱导小鼠川崎病模型研究进展
- Author:
Lichao GAO
;
Fangqi GONG
- Publication Type:Journal Article
- Keywords:
Kawasaki disease;
Coronary arteritis;
Animal models;
Lactobacillus casei cell wall extract
- From:
International Journal of Pediatrics
2014;(5):519-522,523
- CountryChina
- Language:Chinese
-
Abstract:
Kawasaki disease has replaced rheumatic fever as the most common acquired heart disease in childhood,but its etiology remains unknown. The development and analyses of animal models will help us under-stand KD and find new and effective therapeutic strategies for it. Among these existing animal models, mouse modelof coronary artery inflammation induced by a single intraperitoneal injection of lactobacillus casei cell wall extract is a relatively mature model. In this review,we present an overview of how this model established and some progress in research of the mouse model.
