Analysis of plasma hs-CRP,FIB,D-dimer and lipids related indicators in patients with cerebral infarction
10.3969/j.issn.1673-4130.2014.18.007
- VernacularTitle:脑梗死患者 hs-CRP FIB D-二聚体及血脂相关指标检测结果的分析
- Author:
Hongyun ZHENG
;
Yan LI
;
Song LI
- Publication Type:Journal Article
- Keywords:
cerebral infarction;
lipids;
hypersensitive C-reactive protein;
fibrinogen;
D-dimer
- From:
International Journal of Laboratory Medicine
2014;(18):2439-2440,2443
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the lipids related indicators ,high-sensitivity C-reactive protein(hs-CRP) ,FIB and D-dimer levels in cerebral infarction patients .Methods 259 cerebral infraction patients(cerebral infraction group) and 210 healthy individuals(con-trol group) were enrolled in the study .Plasma lipids related indicators such as TC ,TG ,HDL-C ,LDL-C ,ApoA1 ,ApoB ,ApoE levels were measured by enzymatic colorimetric assay .Quantitative fluorescence immunoassay was used to determine serum level of hs-CRP .FIB levels were determined by using coagulation method ,and D-dimer levels by using immune turbidimetric method .Results Compared with the control group ,the TG ,LDL-C ,ApoA1 ,ApoE and hs-CRP levels were significantly higher in the cerebral infarc-tion group(P<0 .01) ,however ,the HDL-C level decreased significantly (P<0 .01) .For TC and ApoB levels ,there were no statis-tical differences between the two groups(P>0 .05) .Conclusion Lipids ,inflammation ,coagulation and fibrinolysis are closely relat-ed in the development of cerebral infarction ,and combined detection helps diagnose cerebral infarction .
