Relationship of lab results and prognosis among children with severe intestinal virus infection
10.3760/cma.j.issn.1008-1372.2014.07.016
- VernacularTitle:重症肠道病毒感染患儿相关检查结果与预后的关系
- Author:
Meiyu YANG
;
Zhiyue XU
- Publication Type:Journal Article
- Keywords:
Child;
Enterovirus infections;
Laboratory techniques and procedures;
Aspartate aminotransferases;
Troponin I;
Leukocyte count;
C-reactive protein;
Prognosis
- From:
Journal of Chinese Physician
2014;(7):913-915,918
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical characteristic of lab results and prognosis of severe intestinal virus infection dis -ease and to provide the objective basis for early intervention .Methods All children who were admitted in pediatric intensive care unit ( PICU) by laboratory diagnosis as cases of severe intestinal virus infection disease in Hunan Children 's Hospital from January 6 to No-vember 25, 2010 were selected as cases of this study .Their medical records were collected .The data was analyzed by χ2 test, Fisher's exact test , and binary logistic regression .Results A percentage ( 33.1%) of patients had abnormal white blood cell ( WBC ) counts, and the difference rates of younger group (under 1 year old) and upper 5 years old group were higher than that in 1~5 years old group with statistically significance (χ2 =12.13, P <0.01).The difference rates of aspartate aminotransferase (AST) and cardiac troponin I(cTnT) were 23.8%and 31.5%, respectively.A percentage (52.9%) of patients had reduced CD4 lymphocytes.Abnor-mal WBC, C reactive protein (CRP), and prognosis have no significant difference ( P >0.05).There were statistically significant differences in procalcitonin (PCT), AST, cTnT anomalies and prognosis ( P <0.01 or P <0.05).Conclusions Abnormal PCT, AST and cTnT are associated with the prognosis of children with severe intestinal virus infection , while WBC and CRP are not .
