Anti-inflammatory mechanism of alpha 7 nicotinic acetylcholine receptors
10.3760/cma.j.issn.1673-4408.2014.04.022
- VernacularTitle:α7烟碱型乙酰胆碱受体的抗炎机制研究进展
- Author:
Tingting WEI
;
Shuangjie LI
- Publication Type:Journal Article
- Keywords:
α7nAChR;
Inflammation;
Chaperones
- From:
International Journal of Pediatrics
2014;(4):415-417,430
- CountryChina
- Language:Chinese
-
Abstract:
Alpha nicotinic acetylcholine receptors(α7nAChR) is a classic neurotransmitter receptor. Re-cent studies have found α7nAChR plays a key role in the cholinergic anti-inflammatory pathway. In this paper, biology characteristics ofα7nAChR molecular,the relationship with cholinergic anti-inflammatory pathway,anti-inflammatory effects of intracellular mechanisms,clinical application are reviewed.