Evaluation of enzyme-linked immunosorbent assay for diagnosing bullous dermatosis
10.3969/j.issn.1671-8348.2014.25.014
- VernacularTitle:酶联免疫吸附试验检测对大疱性皮肤病诊断的评价
- Author:
Yanxi LI
;
Yu DU
;
Yu SHI
- Publication Type:Journal Article
- Keywords:
pemphigus;
pemphigoid,bullous;
enzyme-linked immunosorbent assay
- From:
Chongqing Medicine
2014;(25):3305-3306,3310
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical application and significance of enzyme-linked immunosorbent assay(ELISA)for serologically diagnosing bullous dermatosis.Methods Serum Dsg1,Dsg3 and BP180 expressions were detected in 34 cases of pem-phigus,32 cases of bullous pemphigoid and 33 cases of non-bullous dermatosis by ELISA.Results The sensitivity and specificity of ELISA for detecting the bullous dermatosis antibody were 87.88% and 93.94% respectively.Conclusion The ELISA method has the diagnostic value on bullous dermatosis and the important significance in the disease classification.
