Changes of cytokines in the Cricetulus barabensis and their albino mutant infected with trichinella spiralis
10.3969.j.issn.1671.7856.2014.008.003
- VernacularTitle:旋毛虫感染黑线仓鼠及其白化突变系后细胞因子变化比较分析
- Author:
Xiaofei ZHANG
;
Ran LIU
;
Xiaoxia CUI
;
Shuai MA
;
Xichen ZHANG
;
Jieying BAI
- Publication Type:Journal Article
- Keywords:
Trichinella spiralis;
Cricetulus barabensis;
Albino mutant;
Cytokines
- From:
Chinese Journal of Comparative Medicine
2014;(8):11-15,23
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the differences in immune responses between Cricetulus barabensis and their albino mutant infected with Trichinella spiralis.Methods The physiological parameters of blood , expression levels of IL-2 protein and IL-6 gene in the spleen were analyzed.Results The level of immune cells and cytokines of Cricetulus barabensis was higher than that in the albino mutant .Conclusions Cricetulus barabensis is a suitable model animal for research on long-term latent infection such as infection with Trichinella spiralis.
