Value of fetal tricuspid regurgitation in early screening for chromosomal abnormalities
10.3969/j.issn.1006-5725.2014.14.031
- VernacularTitle:胎儿早孕期三尖瓣反流对染色体异常的诊断价值
- Author:
Hua HAN
;
Jianling LI
;
Fengling CHANG
;
Dandan YANG
;
Songfeng JIA
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Fetal tricuspid regurgitation;
Chromosomal abnormalities;
Congenital heart disease
- From:
The Journal of Practical Medicine
2014;(14):2273-2274,2275
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical significance of fetal tricuspid regurgitation (TR) in the screening of chromosomal abnormalities at the first-trimester. Methods Screening for chromosomal abnormalities was carried out in 1 262 fetuses at 11+0 to 13+6 weeks. Ultrosound was performed to measure crown rump length and nuchal translucency (NT) thickness, and to acquire tricuspid waveform. All the neonates were followed up for 6 months after birth. Results Among the 1 262 fetuses, 68 were found to have TR. TR was present in 54 (4.4%) of the 1 239 chromosomally normal fetuses, and in 14 (61%) of the 23 with chromosomal abnormalities. Cardiac malformations were detectable in 28 fetuses. The prevalence of TR was 64%in those with cardiac malformations and 1.5%in those without cardiac malformations. Conclusions Tricuspid regurgitation is an effective predictor for the detection of fetal chromosomal abnormalities at the first trimester.
