Value of DTI and DTT to differentiate prostate cancer in central gland from benign prostate hyperplasia
10.3969/j.issn.1002-1671.2014.07.024
- VernacularTitle:DTI及DTT在鉴别中央腺区前列腺癌和前列腺增生的价值
- Author:
Tao GONG
;
Shuhui YUAN
;
Guangbin WANG
- Publication Type:Journal Article
- Keywords:
prostate;
magnetic resonance imaging;
diffusion tensor imaging;
apparent diffusion coefficient;
fractional anisotropy;
tractography
- From:
Journal of Practical Radiology
2014;(7):1157-1160,1164
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the ability of diffusion tensor imaging (DTI )and DTT to differentiate the central prostate cancer(PCa )from benign prostate hyperplasia (BPH ).Methods 16 CG-PCa cases and 30 BPH cases proven by Histopathologi-cally had been performed MRI and DTI.ADC values and FA values of CG-PCa and BPH were respectively measured,comparing whether there is any discrepancies between two groups.For DTT maps,two observers record the score using a four-point scale and compare the differences between two groups of lesions about fibers continuity and density.Results ADC values and FA values in BPH-PCa were:(1 357±163)×10-6-(1 058±196)×10-6 mm2/s,and (356±116)×10-3- (407±132)×10-3 respectively. ADC value between the two groups was statistically significant difference (P< 0.05).While FA values was not(P>0.05).Interob-server agreement regarding the scale was good (k =0.723).The two viewers'DTT map score of CG cancer were 2.9±0.9;2.8± 1.0,the BPH were 1.8±0.7;1.7±0.8.The DTT map score between the two groups for two viewers were all statistically signifi-cant difference (P< 0.05).Conclusion ADC values can significantly differentiate CG-PCa from BPH,FA values cannot.DTT maps can describe prostate more institute,providing a certain value in distinguish PCa from BPH.
