Diagnostic significance of three serum indicators in patients with rheumatoid arthritis

VernacularTitle:三种血清指标在类风湿关节炎中的诊断意义
Author: Shuangyin LIANG ; Xianglong ZHUANG ; Baohua WU
Publication Type:Journal Article
Keywords: Rheumatoid arthritis; Anti citrulline antibodies; Anti cytokeratin antibody; Rheumatoid factor
From: Chinese Journal of Immunology 2014;(7):972-973,981
CountryChina
Language:Chinese
Abstract: Objective:To evaluate the value of serum anti citrullinated antibody ( anti CCP-Ab) ,anti keratin antibody ( AKA) and rheumatoid factor ( RF) diagnostic significance of these 3 kinds of index in RA.Methods:256 patients with RA ,92 patients with other autoimmune diseases,50 cases of healthy people were anti CCP-Ab,AKA,RF detection,and the results were analyzed.Results:single target detection ,diagnostic sensitivity of RA from high to low was RF ,anti CCP-Ab,AKA,specific from high to low was AKA ,anti CCP-Ab, RF,anti CCP-Ab and AKA combined detection in clinical diagnostic efficiency.Conclusion: RF,AKA,anti CCP-Ab three index have advantages and disadvantages in diagnosis of RA ,the diagnosis of AKA ,anti CCP-Ab serum of RF negative RA is a powerful complement to,in accordance with the selection of project portfolio appropriate experimental conditions ,the early diagnosis of RA and early treatment ,improve the prognosis had higher value.