Preliminary study on diffusion weighted imaging and LAVA dynamic contrast-enhanced MR imaging(DCE-MRI)of laryngeal and hypopharyngeal carcinoma
10.3969/j.issn.1002-1671.2014.06.006
- VernacularTitle:喉癌和下咽癌 MR 扩散加权成像及动态增强扫描的初步研究
- Author:
Xinyi CHEN
;
Dehong LUO
;
Meng LIN
;
Lin LI
;
Yanfeng ZHAO
;
Han OUYANG
;
Chunwu ZHOU
- Publication Type:Journal Article
- Keywords:
laryngeal carcinoma;
hypopharygeal carcinoma;
magnetic resonance imaging;
dynamic contrast-enhanced imaging
- From:
Journal of Practical Radiology
2014;(6):914-917,925
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the DCE-MRI findings of laryngeal and hypopharyngeal carcinoma.Methods 26 new patients di-agnosed laryngeal and hypopharyngeal cancer by pathology were collected and took DCE-MRI before therapy.The TIC type,ADC value,peak time (Tpeak),peak signal enhancement percentage (SERmax),positive enhancement integral(PEI),maximum slope of increase(MSI)and maximum slope of decrease(MSD)were obtained respectively.These semi-quantitative parameters of primary cancer,normal pharyngeal tissue and the same layer neck muscles were compared and P <0.05 was considered statistical signifi-cance.Results The TIC types for primary tumor including type Ⅰ(5),type Ⅱ(6),type Ⅲ(1 5),a significant difference of Tpeak、MSI、MSD were observed(P < 0.05 )no difference in ADC values (P > 0.05 )was found.Different b values (b = 300 s/mm2 , 500 s/mm2 )for ADC values were significantly different.There was statistical significance in semi-parameters among the primary cancer,normal pharyngeal wall tissue and the same layer neck muscles.Setting MSI value 58.32 threshold to distinguish abnormal and normal tissues,sensitivity and specificity both were 84.6%.Conclusion DCE-MRI can reflect morphology and signal differences among neck muscles,normal and abnormal laryngeal and hypopharyngeal tissues,providing help for diagnosis of primary carcino-ma.
