The expression of Ezrin and its correlation in nontraumatic osteonecrosis of femoral head
- VernacularTitle:非创伤性股骨头坏死组织中Ezrin表达的相关性研究
- Author:
Zhengliang LUO
;
Xu LI
;
Xifu SHANG
- Publication Type:Journal Article
- Keywords:
nontraumatic osteonecrosis of femoral head;
Ezrin;
correlation
- From:
Acta Universitatis Medicinalis Anhui
2014;(6):826-828,829
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression level of Ezrin and its clinical significance in nontraumatic os-teonecrosis of femoral head. Methods Expression level of Ezrin in 38 patients with nontraumatic osteonecrosis of femoral head ( experimental group) and 16 patients with femoral neck fractures ( control group) were detected by immunohistochemistry and RT-PCR analysis. Results The expression level of Ezrin was significantly lower in ex-perimental group than that in control group (P<0. 05). It was correlated with the Ficat Stage, and had no rela-tionship with gender, age, BMI, profession and etiological factor. Conclusion Ezrin may involve in the develop-ment of nontraumatic osteonecrosis of femoral head, and play an important role in regulation.
