Effects of statins on serum lipids in patients with coronary heart disease risk factors and impact analysis
10.3760/cma.j.issn.1008-6706.2014.14.035
- VernacularTitle:辛伐他汀对冠心病患者血脂水平影响及相关因素分析
- Author:
Ming ZHOU
;
Manrong TIAN
- Publication Type:Journal Article
- Keywords:
Coronary heart disease;
Blood lipid;
Simvastatin
- From:
Chinese Journal of Primary Medicine and Pharmacy
2014;(14):2162-2163,2164
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of statins on coronary artery disease in patients with coro-nary heart disease and lipid regulating effect on curative effect .Methods 126 cases of patients with coronary heart disease were randomly divided into the control group of 60 cases and 66 cases in the treatment group ,the control group was given routine treatment of coronary heart disease ,the treatment group was treated with routine treatment with simv-astatin bedtime,before treatment and after 3,12 months when the determination of lipids ,liver function and renal func-tion index,and compared between the two groups of cardiovascular events .Results 3 months after treatment , TG, TC,LDL-C of the treatment group decreased significantly ,while the control group in 3,12 months after treatment,TC, TG,LDL-C had the rise of certain level(t=5.43,5.21,4.85,all P<0.05).The two groups after treatment in 3, 12 months in TC,TG,LDL-C had significant differences(t=5.32,5.78,5.64,6.15,6.41,6.06,all P<0.05).Dur-ing follow-up,patients in the treatment group 33 cases of cardiovascular events ,the control group of 81 cases,two groups of cardiovascular event rate had a significant difference (χ2 =13.42,P<0.01).Conclusion Statins can re-duce blood lipids in patients with coronary artery disease ,thereby reducing the patients appear related to cardiovascu-lar accidents,improve the treatment effect of coronary heart disease .
