Main pathogenic bacteria and drug resistance in Affiliated Hospital of Academy of Military Medical Sciences between 2012 and 2013
10.7644/j.issn.1674-9960.2014.05.010
- VernacularTitle:2012~2013年军事医学科学院附属医院主要病原菌分布及耐药性分析
- Author:
Xiuyun YIN
;
Nong YU
;
Lijun ZENG
;
Qian JIANG
;
Lin WANG
;
Yihe LI
;
Shiping SONG
;
Wei ZHANG
;
Jiankui CHEN
;
Shuiping CHEN
- Publication Type:Journal Article
- Keywords:
pathogenic bacteria;
antibiotics;
drug resistance,bacterial
- From:
Military Medical Sciences
2014;(5):365-367,370
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the flora distribution and drug resistance status in the Affiliated Hospital of Academy of Military Medical Sciences so as to provide experimental data for clinical doctors to use antibiotics more efficiently.Methods The clinical data of pathogenic bacterial infections over nearly one year in our hospital were retro -spectively analyzed .Results There were 3815 strains of pathogenic bacteria isolated from the sample .The percentage of Gram-positive strains was 36.4%while that of Gram-negative bacteria was 63.6%.The most common bacteria were Esche-richia coli, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa and Staphylococcus epidermidis.In terms of drug tolerance , Enterobacteriaceae remained highily sensitive to carbapenems .The total resistance rate was 2%-5%.The resistance rate of A.baumannii to meropenem and imipenem was 60%.There were still a few pan-drug resistant strains among K.pneumoniae,A.baumannii and P.aeruginosa,but there were no drug resistant strains to vancomycin , tige-cycline and linezolid in Staphylococcus.The resistance rate of Enterococcus faecium to vancomycin was 9%.The bacteria were distributed predominantly in ICU ,Department of Hematology and Department of Oncology .The samples were mainly composed of phlegm specimens .Conclusion The high distribution in the three departments mentioned above is largely re-lated to the diseases being treated .The specimens from the lower respiratory tract show more types of bacteria that are mostly drug-resistant, and the isolating rate of vancomycin resistant Enterococcus and carbapenems resistant K.pneumoniat is com-paratively high .