The value of MRI combined with serum CA125 test in the diagnosis of ovarian tumor

VernacularTitle:磁共振成像结合血清CA125水平检测在卵巢肿瘤诊断中的价值
Author: Mingwei MAO ; Lu YANG ; Min LI ; Hong YU ; Zhimin LIU
Publication Type:Journal Article
Keywords: Ovarian neoplasms; Magnetic resonance imaging; CA125; Diagnosis
From: Cancer Research and Clinic 2014;26(5):315-317,321
CountryChina
Language:Chinese
Abstract: Objective To investigate the value of MRI combined with serum CA125 test in the diagnose of ovarian tumor.Methods To investigate the MRI and serum CA125 level of healthy control group (40 cases),benign tumor group (52 cases),and the malignant tumor group (43 cases).Results Of 95 patients with ovarian masses,CA125 was detected in the malignant patients with the sensitivity of 79.3 ％,specificity of 72.6 ％ and accuracy of 75.1％.MRI was 73.8 ％,81.2 ％,and 82.6 ％ respectively.Combined with CA125 and MRI was 69.4 ％,97.3 ％,and 88.6 ％.Youden' s index of combined detection was significantly higher than single detection (MRI combined with CA125 and single MRI u =1.97,P =0.012 5,and CA125 u =1.96,P =0.012 0).Conclusion MRI combined with CA125 could improve the accuracy of diagnosis ovarian neoplasm in clinic.