Obesity and Gallbladder Diseases.
- Author:
Seung Uk JEONG
1
;
Sung Koo LEE
Author Information
- Publication Type:English Abstract ; Review
- Keywords: Obesity; Gallbladder diseases
- MeSH: Body Mass Index; Cholecystitis/etiology; Exercise; Gallbladder Diseases/drug therapy/epidemiology/*etiology/prevention & control; Gallbladder Neoplasms/epidemiology/etiology; Gallstones/epidemiology/etiology; Humans; Hyperinsulinism; Hypolipidemic Agents/therapeutic use; Insulin Resistance; Obesity/*complications; Ursodeoxycholic Acid/therapeutic use; Weight Loss
- From:The Korean Journal of Gastroenterology 2012;59(1):27-34
- CountryRepublic of Korea
- Language:Korean
- Abstract: Obesity is an important health problem in the world and related to many critical diseases, such as diabetes, cardiovascular disease, and metabolic syndrome. Obesity leads to fat infiltration of multiple organs and infiltrated adipose tissue produces many cytokines resulting in the dysfunction of organs such as the gallbladder. In the biliary diseases, obesity and overweight have been known as a major risk factor for gallstones. According to current studies, obesity, insulin resistance, hyperinsulinemia, and metabolic syndrome are related to various gallbladder diseases including gallbladder stones, cholecystitis, gallbladder polyps, and gallbladder cancers. We reviewed further literature on the obesity and gallbladder diseases, in aspects of epidemiology, mechanism, pathology and prevention.
