Application analysis of coronary angiography combined with FFR in percutaneous coronary intervention treatment of coronary artery disease
10.3969/j.issn.1671-8348.2014.12.011
- VernacularTitle:冠状动脉造影联合 FFR在冠心病介入治疗中的应用分析
- Author:
Fengbo REN
;
Junming LIU
;
Yan LIANG
;
Wenjun HUANG
;
Wei XIE
;
Xia GAO
;
Ke LI
;
Mingjian WANG
;
Liang ZHAO
- Publication Type:Journal Article
- Keywords:
coronary disease;
coronary angiography;
fractional flow reserve,myocardial;
percutaneous coronary intervention
- From:
Chongqing Medicine
2014;(12):1439-1441,1444
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical application value of coronary angiography (CAG) combined with fractional flow re-serve(FFR) in percutaneous coronary intervention treatment of coronary artery disease (CAD) .Methods 82 cases of CAD(147 le-sions) with single hemadostenosis at least 70% -90% were randomized into the observation group and the control group .The ob-servation group(40 cases ,72 lesions) was performed the myocardial FFR detection by the pressure guide wire and the drug-eluting stents(DES) were placed in the lesions only if FFR ≤0 .80 .The patients with postoperative FFR ≤0 .80 were given the in-stent post-balloon dilatation .The control group(42 cases ,75 lesions) underwent the percutaneous coronary intervention(PCI) for conduc-ting the routine DES implantation .The general condition ,risk factors(hypertension ,diabetese ,hyperlipidemia ,smoking ,etc .) ,num-ber of lesions ,implanted stents ,hospitalization cost ,occurrence rate of major adverse cardiac events (MACE) after postoperative 6 months and the angina recurrence rate were compared between the two groups .Results The number of used stents per patient and the hospitalization cost in the observation group were significantly lower than those in the control group [(0 .88 ± 0 .88) vs .(1 .81 ± 0 .83) ,(47 200 ± 2 3000)Yuan vs .(60 000 ± 2 4100)Yuan P< 0 .05] .The two groups had no all-cause death in postoperative 6-months .The recurrent myocardial infarction rate ,revascularization rate and recurrent angina in the two groups were 2 .50% vs .0 , 2 .50% vs .2 .38% and 5 .00% vs .7 .14% respectively ,the differences had no statistical significance(P>0 .05) .Conclusion CAG combined with FFR detection can significantly reduce the number of stents and the hospitalization cost without increasing the occur-rence rates of MACE and angina within postoperative 6 months in CAD patients .
