Analysis on laboratory index characteristics of pulmonary hypertension patients with different function states and pressure stages
10.3969/j.issn.1671-8348.2014.10.007
- VernacularTitle:不同功能状态和压力分级的肺动脉高压患者实验室指标特征分析
- Author:
Lu GUO
;
Jie ZENG
;
Yuejian LIU
;
Zhengliang XIE
;
Chunmei LI
;
Yang YANG
;
Zhongwei ZHOU
;
Xiaoshu LIU
;
Jun ZOU
- Publication Type:Journal Article
- Keywords:
hypertension,pulmonary;
blood gas analysis;
natriuretic peptide,brain;
hemoglobins,abnormal;
erythrocyte sedimen-tation rate;
C-reactive protein
- From:
Chongqing Medicine
2014;(10):1175-1177,1180
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the laboratory index characteristics of pulmonary hypertention (PH ) patients with different function states and pressure stages .Methods 2 752 patients diagnosed with PH in the outpatient department ,emergency depart-ment and inpatient department of this hospital from January 2006 to December 2011 were retrospectively analyzed .The clinical as-sessment of the disease condition was done according to the function state and pressure stage of PH recommended by WHO .The characteristics of hematological indexes ,inflammatory indicators and blood gas analysis were observed as well .Results The most common hematological abnormal indexes were the serum brain natriuretic peptide (BNP) elevation(89 .12% ) ,abnormal liver func-tion(58 .32% ) and abnormal hemoglobin(58 .32% ) .The proportion of the PH patients with the elevation of erythrocyte sedimenta-tion rate(ESR) and high-sensitivity C-reactive protein (hs-CRP) were 78 .52% and 73 .59% respectively .The constituent ratio of the BNP increase ,liver function abnormality ,abnormal hemoglobin ,elevation of UA and ESR had statistical differences among the PH patients with different function states and pressure stages (P<0 .05) .The most commonly blood gas analysis abnormality was hypoxemia(83 .08% ) .Respiratory alkalosis had the highest incidence rate in the acid-base imbalance(24 .58% ) .Conclusion The most common hematological abnormal indexes among PH patients are the elevation of serum BNP ,abnormal liver function and he-moglobin abnormality .The laboratory abnormal indexes of above 3 items and the increase of UA and ESR are always related with the severity of disease ,which should to be followed-up .
