Research on the tumor suppression of Chinese caterpillar fungus water decoction combined cisplatin on tumor burdened mice
10.3969/j.issn.1671-8348.2014.15.025
- VernacularTitle:冬虫夏草水煎剂联合顺铂对荷瘤小鼠抑瘤作用的实验研究
- Author:
Zhan HUANG
;
Yin TIAN
;
Huaijing LI
;
Guixia QU
;
Qinglin JIANG
- Publication Type:Journal Article
- Keywords:
Chinese caterpillar fungus water decoction;
secondary tumor suppression effect;
a tumor burdened mice
- From:
Chongqing Medicine
2014;(15):1896-1897,1900
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the tumor suppression of Chinese caterpillar fungus water decoction combined cisplatin on a tumor burdened mice .Methods The beforehand vaccinal HCT8 tumor burdened mice were randomly devided into 5 groups(n=10) ,then 3 groups of Chinese caterpillar fungus water decoction were given a tumor burdened mice stomach (2 .5 ,5 .0 ,10 g/kg) ,1 times a day ,12 d .1 group of mice were given saline .1 group were given cisplatin .Determination of different concentrations of cordyceps water decoction lavage ,then observe the changes of tumor‐burdened bone tumors in mice weight .Results For vaccination HCT8 tumor burdened bone tumors had an average weight of each dose group mice compared with saline group have significant difference(P<0 .01) ,while Chinese caterpillar fungus water decoction (2 .5 ,5 .0 g/kg) and cisplatin group mice tumor block is more significant difference(P< 0 .01) ,the tumors had the lighter weight .Conclusion Chinese caterpillar fungus water decoction has tumor suppression effect on tumor burdened mice .
