Contrast of curative effects between extended full-thickness transanal local excision and traditional laparotomy for early stage low rectal cancer
10.3760/cma.j.issn.1006-9801.2014.03.003
- VernacularTitle:经肛门局部扩大全层切除术与传统开腹手术治疗早期低位直肠癌的效果比较
- Author:
Fa FANG
;
Haijiang WANG
- Publication Type:Journal Article
- Keywords:
Rectal neoplasms;
Laparotomy;
Survival rate;
Extended full-thickness transanal local excision;
Controlled clinical trial
- From:
Cancer Research and Clinic
2014;26(3):153-155,159
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the advantages and prognosis of extended full-thickness transanal local excision in treating early stage low rectal cancer.Methods Clinical gastrointestinal surgery data of transanal local excision surgeries of 163 patients from January 2003 to December 2010 was reviewed.According to the different operation modes,the patients were divided into group A (transanal local expanded full-thickness resection group,78 cases),group B (traditional open operation group,85 cases),to observe the operation status and survival time.Results The operative time [(43.17±12.31) min vs (216.41±60.12) min,t =12.924,P =0.011],the volume of bleeding (30 ml vs 110 ml,Z =-2.522,P =0.012),the postoperative intestinal function recovery time [(1.61±0.76) d vs (3.72±1.46) d,t =2.681,P =0.037),the postoperative hospital stay [(5.39±1.21) d vs (22.79±8.31) d,t =6.964,P =0.023),the rate of complication [3.85 ％ (3/78)vs 24.71％ (21/85),x2 =14.096,P ＜ 0.001] of group A and group B showed statistical significance (P ＜ 0.05),1 year,3 years,5 years survival rate of group A and group B were 100.0 ％,93.5 ％,89.5 ％ and 98.8 ％,95.2 ％,90.3 ％ respectively,the average survival time were respectively 57.08 months and 57.49 months,with no statistical difference (P ＞ 0.05).Conclusions The extended full-thickness transanal local excision in treating early stage low rectal cancer can achieve the effect of laparotomy.Compared with laparotomy,it has more advantages such as shorter operative time,less bleeding,less invasive,faster postoperative recovery,and fewer occurrences of complications.
