Detection of carbapenemase-resistant genes in multi-drug resistant Acinetobacter baumannii
10.3969/j.issn.1673-4130.2014.10.003
- VernacularTitle:多重耐药鲍氏不动杆菌的碳青霉烯酶耐药基因的检测
- Author:
Rui HU
;
Shuiying LU
;
Xiuyu ZHANG
;
Changwu HUANG
;
Weixian CHEN
- Publication Type:Journal Article
- Keywords:
A cinetobacter baumannii;
drug resistance,multiple;
gene
- From:
International Journal of Laboratory Medicine
2014;(10):1238-1239,1242
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the distribution of carbapenemase-resistant genes carried by multi-drug resistant Acineto-bacter baumannii .Methods 80 strains of multi-drug resistant Acinetobacter baumannii were collected .Polymerase chain reaction (PCR)wasusedtodetectcarbapenemase-resistantgenes,suchasOXA-23,OXA-24,OXA-51,OXA-58,SIM,IMP,VIM ,GIMand SPM ,in multi-drug resistant Acinetobacter baumannii .Results Drug resistant gene OXA-23 [49 (61 .3% )] ,OXA-51 [73 (91 .3% )] ,OXA-58[7(8 .8% )] ,OXA-24[1(1 .3% )] ,IMP[17(21 .3% )] and VIM[2(2 .5% )] were found in 80 strains of multi-drug resistant Acinetobacter baumannii ,while GIM ,SIM and SPM gene were not found .Conclusion IMP ,OXA ,VIM is the main genotypes carried by multi-drug resistant Acinetobacter baumannii .
