Identification of rare Nocardia otitidiscaviarum and its drug sensitivity analysis
10.3969/j.issn.1673-4130.2014.10.038
- VernacularTitle:罕见豚鼠耳炎奴卡菌的鉴定及其药物敏感性分析
- Author:
Wei ZHANG
;
Guojun PENG
;
Jia LIU
;
Hongyan HU
;
Hui LIANG
- Publication Type:Journal Article
- Keywords:
16S rRNA;
sequence analysis;
Nocardia otitidiscaviarum
- From:
International Journal of Laboratory Medicine
2014;(10):1320-1321,1325
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the identification of rare Nocardiaotitidiscaviarum and its drug sensitivity .Methods Morpho-logical ,physiological and biochemical phenotype identification methods combined with 16S rRNA sequence analysis were employed to identified the bacteria strains .Broth method was used to detect their drug sensitivity .Results The clinically isolated Nocardia strain was identified as Nocardiaotitidiscaviarum which was resistant to piperacillin ,erythromycin ,ceftazidime ,cefoperazone ,gen-tamicin ,cefoxitin ,piperacillin/tazobactam ,and was sensitive to vancomycin ,levofloxacin ,imipenem ,etimicin ,ciprofloxacin ,amika-cin ,sulfamethoxazole .Conclusion 16S rRNA gene sequence analysis can be used to identify Nocardia otitidiscaviarum ,and sulfa drugs shows good therapeutic effect .