Evaluation of measurement uncertainty in routine coagulation assays in medical laboratory
10.3969/j.issn.1673-4130.2014.08.025
- VernacularTitle:医学实验室常规凝血检验项目测量不确定度的评定
- Author:
Nengbing YAN
;
Hui LV
;
Junfeng LI
;
Youjun PI
;
Shiyong HAO
- Publication Type:Journal Article
- Keywords:
coagulation assay;
measurement uncertainty;
assessment
- From:
International Journal of Laboratory Medicine
2014;(8):997-998,1000
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the application of evaluation of measurement uncertainty in routine coagulation assays based on the data of internal quality control (IQC) and results of external quality assessment (EQA) .Methods Data of clinical coagulation assays of clinical laboratory of Xiangyang city hospital were collected ,Which came from six months of IQC and 3 times of EQA of ministry of health clinical laboratory center from 2012 to 2013 .The combined and expanded uncertainties of 3 measurements(PT , APTT and Fbg) were evaluated according to CNAS top-downapproach .Results When PT were in 12 .72 s and 21 .04 s ,its ex-panded uncertainty were 1 .06 s and 1 .96 s ,and APTT in 36 .6 s and 50 .6 s were 2 .59 s and 5 .30 s ,and Fbg in 3 .32 g/L was 0 .30 g/L .Conclusion Evaluation of measurement uncertainty by using internal quality control data and EQA results for routine coagula-tion detection index is economical and practical and acceptable way ,with good clinical practice .
