Optimization of Alcohol Extraction Technique for Rhizoma Corydalis and Salvia Miltiorrhiza by Orthogonal Test
- VernacularTitle:正交试验法优选延胡索及丹参的醇提工艺条件
- Author:
Haolin XIE
;
Min YU
;
Lianqing JIAO
- Publication Type:Journal Article
- Keywords:
Rhizoma Corydalis;
Salvia miltiorrhiza;
Extraction process;
Orthogonal test;
HPLC
- From:
China Pharmacist
2014;(4):695-696,697
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To optimize the ethanol extraction process of Rhizoma Corydalis and Salvia miltiorrhiza, and study the effect of comminution degree of the medicinal materials on the effective constituent. Methods:Using the alcohol concentration, alcohol vol-ume, extraction time and extraction times as the impacting factors,the content of tetrahydropalmatine and salvianolic acid as the indi-ces, the extraction process was optimized by orthogonal test of L9(34). Results:The best extraction conditions were as follows:Rhizo-ma Corydalis was crushed into coarse powder, the material / liquid ratio was 1∶6 with 75% ethanol as the extraction solvent,extracting twice with 1. 5h each. Conclusion:The extraction method is appropriate and simple,and can be used in the industrial production.
