Clinical Observation of Xiaoxianxiong Decoction Combined with Metformin in Treating Phlegm-heat Type 2 Diabetic Patients
10.3969/j.issn.1005-5304.2014.02.009
- VernacularTitle:小陷胸汤联合盐酸二甲双胍片治疗2型糖尿病痰湿蕴热型临床观察
- Author:
Limin ZHANG
;
Yi TAN
;
Wei HUANG
;
Xueying ZHANG
;
Guanqiang LI
;
Deyong FENG
- Publication Type:Journal Article
- Keywords:
diabetic;
phlegm-heat;
glucose and lipid metabolism;
Xiaoxianxiong Decoction;
metformin
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2014;(2):32-34,38
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of Xiaoxianxiong Decoction combined with metformin on glucose and lipid metabolism of phlegm-heat type 2 diabetic patients (T2DM). Methods Totally 104 phlegm-heat T2DM patients were randomly divided into two groups (each contains 52 cases), and given the diabetes lifestyle intervention. Control group additionally took 0.5 g metformin twice daily. And treatment group, besides taking 0.5 g metformin, was given Xiaoxianxiong Decoction, one dose and three times per day warmly. After 12 weeks, FBG, HbA1C, TC, TG, HDL-C, LDL-C, 2 hPG of the two groups were determined, and the therapeutic effect was evaluated. Results The total effective rate in the treatment group was 92.31%, and 76.92%in control group (P<0.01). The difference in symptom score, FBG, 2 hPG, TC, TG, HDL-C and LDL-C between the two group were significant, so as that between before and after treatment of both groups (P<0.05). Conclusion Xiaoxianxiong Decoction combined with metformin can effectively lower the levels of blood glucose and blood lipid in phlegm-heat T2DM patients, enhance the therapeutic effect and improve the metabolism of glucose and lipid.
