Clinical Efficacy and Related Influencing Factors of Jianpi Huatan Decoction Plus Zhongwan Moxibustion in Patients with Mild to Moderate Stable COPD
10.3969/j.issn.1005-5304.2014.03.009
- VernacularTitle:健脾化痰方配合温灸中脘治疗轻中度稳定期慢性阻塞性肺疾病临床疗效及相关影响因素分析
- Author:
Ping ZHANG
;
Huan WU
;
Quan LIU
;
Ruobing SHEN
;
Xiaoping YU
- Publication Type:Journal Article
- Keywords:
Jianpi Huatan Decoction;
moxibustion;
Zhongwan (RN12);
stable COPD;
quality of life;
regression analysis
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2014;(3):29-32,108
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy of Jianpi Huatan Decoction plus Zhongwan (RN12) moxibustion on patients of mild to moderate stable chronic obstructive pulmonary disease (COPD) with syndrome of qi deficiency of lung and spleen, and analyze the related influencing factors. Methods With prospective randomized clinical trial, 140 cases of mild to moderate stable COPD were randomized into two groups (70 cases for each group). Treatment group was treated by Jianpi Huatan Decoction plus Zhongwan moxibustion based on western medicine, and control group was only treated by western medicine. Both groups were treated for 12 weeks and followed up for 12 weeks. Scores of clinical symptoms and quality of life questionnaire were examined, and multiple logistic regression analysis was used to find possible impacting factors on the effect. Results Symptoms were significantly alleviated after treatment (P<0.01) in both groups. The clinical effects and quality of life in treatment group were significantly improved than the control group (P<0.01). There were no significant changes in life quality of control group ( P>0.05). Multiple logistic regression analysis showed that different therapies and severity of COPD were the major influencing factors of clinical effect (P<0.05, P<0.01). Conclusion Jianpi Huatan Decoction plus Zhongwan moxibustion had significant therapeutic effect on mild to moderate stable COPD patients with syndrome of qi deficiency of lung and spleen by alleviating symptoms and improving quality of life. Treatment style and severity of COPD are the main influencing factors.
