Combined prognostic utility of NT-proBNP and hs-CTNI in NSTE-ACS risk stratification and its therapy
10.3969/j.issn.1671-8348.2013.28.017
- VernacularTitle:NT-proBNP和hs-CTNI联合检测在急性非ST段抬高型冠状动脉综合征危险分层及治疗中的意义
- Author:
Ya LI
;
Tao GENG
;
Yongxin LIU
;
Bingxun WANG
;
Shipeng DAI
;
Jiangang ZHANG
;
Wanzhong PENG
;
Zesheng XU
- Publication Type:Journal Article
- Keywords:
N-terminal pro-B-type natriuretic peptide;
high-sensitive troponin;
acute non-ST segment elevation coronary syn-drome;
percutaneous coronary intervention;
coronary artery bypass surgery
- From:
Chongqing Medicine
2013;(28):3377-3378,3381
- CountryChina
- Language:Chinese
-
Abstract:
Objective To research the combined prognostic utility of NT-proBNP and hs-CTNI in NSTE-ACS risk stratification and early intervention therapy .Methods A total of 245 NSTE-ACS patients were divided to 4 groups(Aa ,Ab ,Ba ,Bb groups) ac-cording to immediate admission NT-proBNP and hs-CTNI .Patients were accepted percutaneous coronary intervention (PCI) ,coro-nary artery bypass grafting and conservative treatment were taken 6 months follow-up .Results The heart failure incidence of Aa group was significantly higher than Ba group(P<0 .05) .6 patients happened left main lesion or multivessel lesion in Aa group were obviously higher than other groups .The incidence of Bb group accepted PCI was obviously higher than Aa group (P<0 .05) .Bb group patients were accepted PCI earlier than other groups ,there was no significance(P>0 .05) .In 6 months follow-up ,5 patients died and 10 patients accepted revascularization again because of severe angina and AMI .Conclusion In NSTE-ACS patient ,NT-proBNP and hs-CTNI elevation was closely related with severe coronary lesions and worse prediction ,which could undergo early in-tervention therapy .
