Investigation on bioavailability and biogical equivalence of 3 amoxicilline products
- Author:
Bui Tung Hiep
- Publication Type:Journal Article
- Keywords:
bioavailability, amoxicilline
- MeSH:
Biological Availability;
Amoxicillin;
Therapeutics
- From:Pharmaceutical Journal
2004;44(12):21-24
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The study was carried out on 18 healthy volunteers (9 men and 9 women), from 21 - 36 years old, all of them don’t be alcohol and smoke addiction. The result: in the experience condition, the plasma concentration of amoxcilin while using 1000mg tablet, 2 times/24 hours is higher than dose 500mg, 3 times/24 hours for both tablet and capsule. The treatment regimen based on 500mg tablet, 3 times/24 hours ensures more rapid absorption than on 500mg capsule, but it don’t change the bioavailable and the bioequivalence of drug