Clinical Effects Evaluation of Huoxue Dingxuan Capsules in Treatment of Vertebral Artery Type of Cervical Spondylosis
10.3969/j.issn.1005-5304.2014.01.011
- VernacularTitle:活血定眩胶囊治疗椎动脉型颈椎病临床疗效评价
- Author:
Wantao DONG
;
Min SONG
;
Zebin LV
;
Wenbo AN
;
Xiaoming WEN
;
Yiwei JIANG
;
Bingxiong CHEN
;
Jutang CHAI
- Publication Type:Journal Article
- Keywords:
vertebral artery type of cervical spondylosis;
Huoxue Dingxuan Capsule;
randomized controlled trial;
clinical effects evaluation
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2014;(1):33-35,39
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical effects of Huoxue Dingxuan Capsules on treatment of vertebral artery type of cervical spondylosis, and evaluate its efficacy and safety. Methods Totally 130 cases of vertebral artery type of cervical spondylosis were randomly assigned to treatment group and control group, and treated with Huoxue Dingxuan Capsules and Sibelium capsules respectively. Integration method was used to compare the differences of main symptoms and signs, the overall efficacy and safety were evaluated, and relapse after six months was followed up. Results Both groups had a significant effect on the improvement of signs and symptoms in vertebral artery type of cervical spondylosis, the total efficiency was 94.03%(63/67) in treatment group and 82.54% (52/63) in control group. The treatment group had a better effect on the overall efficacy and relieving symptoms and signs compared with the control group (P<0.01). The mean blood flow velocity had a significant change after treatment (P<0.05), and the treatment group was better than the control group (P<0.01). Within six months, the treatment group had 4 cases (6.34%) with mild recurrence of symptoms and signs, and the control group had 18 cases (34.61%), the difference between the two groups was statistically significant (P<0.05), and no severe recurrence was found. The two groups showed no side effects. Conclusion Huoxue Dingxuan Capsules is safe and effective for treating vertebral artery type of cervical spondylosis, and the long-term efficacy and subjects’ compliance are better than oral Sibelium capsules.
