Iterative Reconstruction Algorithm CT Perfusion and Angiography in the Diagnosis of Ischemic Cerebrovascular Disease
10.3969/j.issn.1005-5185.2013.12.001
- VernacularTitle:迭代重建算法CT灌注成像与CT血管造影在缺血性脑血管病中的诊断价值
- Author:
Peijun LI
;
Biao HUANG
;
Changhong LIANG
;
Wenzhen ZHU
;
Jieying FENG
;
Xiaoling ZHONG
- Publication Type:Journal Article
- Keywords:
Brain ischemia;
Stroke;
Tomography,spiral computed;
Perfusion weighted imaging;
Cerebral angiography;
Iterative reconstruction algorithm;
Radiation dosage
- From:
Chinese Journal of Medical Imaging
2013;(12):881-885,890
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To reconstruct perfusion computerized tomography angiography (PCTA) images from the volume data of low-dose brain CT perfusion scan with iterative reconstruction algorithm, to analyze the capability of PCTA on the display of brain arteries, and to explore the methods to reduce the radiation dose for stroke CT examinations. Materials and Methods This was a prospective study, 55 patients (605 arterial segments) with clinical diagnosis of ischemic cerebrovascular disease underwent cranial CT scan, iterative algorithm low-dose brain CT perfusion scan and conventional cranial CTA examinations using a 256-slice spiral CT. 11 segments of the cerebral artery in each case were analyzed using conventional CTA results as the reference standard to assess the display of brain arteries in PCTA. Results Effective dose of CT perfusion scan was 2.12 mSv. Among the 580 vessel segments which CTA showed no stenosis or stenosis<30%, only one vessel segment of PCTA was inconsistent with CTA; among the 19 vessel segments which CTA showed stenosis≥30%but not occluded, results of 12 vessel segments in PCTA were consistent with CTA, while the stenosis states were exaggerated by PCTA in the other seven vessel segments;results of the two methods were consistent in six vessel segments which was found occluded by CTA. Kw values were >0.75 for the consistency test between PCTA and CTA on the display of brain arteries. Conclusion Radiation dose of iterative algorithm cranial CT perfusion scan is significantly lower, and the images reconstructed from the volume data of perfusion CT are highly consistent with the CTA results, thus are able to meet the needs of the clinical diagnosis.
