Stability of Shuanghuanglian Injection Mixed with Cefazolin Sodium and Other Injections in Vitro
10.3969/j.issn.1005-5304.2013.10.022
- VernacularTitle:双黄连注射液与注射用头孢唑啉钠等体外配伍稳定性研究
- Author:
Li ZHANG
;
Fujun QU
;
Yan LIU
;
Zhimin DU
- Publication Type:Journal Article
- Keywords:
Shuanghuanglian Injection;
Cefazolin Sodium for Injection;
Dexamethasone Sodium Phosphate Injection;
Ribavirin Injection;
drug combination;
drug stability
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2013;(10):63-64,65
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the compatibility of Shuanghuanglian Injection mixed with Cefazolin Sodium for Injection, Dexamethasone Sodium Phosphate Injection and Ribavirin Injection. Methods Under room temperature, the changes of appearance were determined by pH meter and particle counter for Shuanghuanglian Injection mixed with Cefazolin Sodium for Injection, Dexamethasone Sodium Phosphate Injection and Ribavirin Injection. Results There were no evident changes in appearance and pH of Shuanghuanglian Injection mixed with Cefazolin Sodium for Injection, Dexamethasone Sodium Phosphate Injection and Ribavirin Injection. The number of particles (diameter≥25 μm) of Shuanghuanglian Injection mixed with Cefazolin Sodium for Injection and Dexamethasone Sodium Phosphate Injection was increased after 0.5 h. Conclusion Shuanghuanglian Injection can be mixed with Cefazolin Sodium for Injection, Dexamethasone Sodium Phosphate Injection and Ribavirin Injection for bigeminy, while should not for multitherapy.
