Determination of Atractylodin in Essential Oil of Jingfukang Preparations and Stability in Different Solutions
10.3969/j.issn.1005-5304.2013.07.020
- VernacularTitle:颈复康制剂挥发油中苍术素含量测定及其在不同介质中稳定性研究
- Author:
Dongli YANG
;
Chunmin WANG
;
Jingli LIU
;
Xiaowei XU
;
Ruimin LI
;
Cheng WANG
- Publication Type:Journal Article
- Keywords:
atractylodin;
stability;
GC;
Jingfukang preparations
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2013;(7):55-56,57
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a method for determination of atractylodin in essential oil of Jingfukang preparations by GC and analyze its stability in different solutions. Methods Using HP-5 quartz capillary column (30 m×0.32 mm), programmed temperature was conducted with the FID as detector. The content of atractylodin was determined both at room temperature and 4 ℃ in 20 days. Results The linear range of atractylodin was 4.172-41.72 μg/mL (r=0.999 7). The stability of atractylodin in essential oil of atractylodes was better than in anhydrous alcohol solution or in essential oil of Jingfukang preparation. Conclusion This method is suitable for the quality control of atractylodin in essential oil of Jingfukang preparations. Low temperature is helpful to the stability of atractylodin. The storage period of essential oil of Jingfukang preparations should not be too long.
