The evaluation of efficacy and safety of nicorandil on coronary slow flow phenomenon

VernacularTitle:应用尼可地尔治疗冠状动脉慢血流现象的疗效及安全性评价
Author: Jianming ZHANG ; Feng ZHU ; Huaming MU ; Xiaohua PANG ; Jianjun YANG ; Zhongjie WU ; Qing MI
Publication Type:Journal Article
Keywords: nicorandil; coronary angiography; coronary slow flow phenomenon
From: Chongqing Medicine 2013;(24):2869-2870,2872
CountryChina
Language:Chinese
Abstract: Objective To evaluate the effect and safety of nicorandil on Coronary Slow Flow Phenomenon (CSFP) .Methods The CSFP patients(n=60) were randomly divided into the control group treated with placebo and the treatment group treated with nicorandil .The changes of the clinical symptoms ,the frequency and duration of pectoralgia ,the six-minute walk test ,and TIMI frame counts were observed before and after treatment .Results The treatment group had a better therapeutic effect than the con-trol group(P<0 .05) .There were significant differences in the frequency and duration of pectoralgia ,the six-minute walk test ,and TIMI frame counts in treatment group before and after treatment ,which were superior to those of control group (P<0 .05 ,P<0 .01) .The blood routine examinations and hepatorenal function were within the normal range before and after treatment .Conclusion Nicorandil has better therapeutic effect and safety on CSFP .