Treatment of obstructive jaundice by percutaneous biliary puncture combined with intensity modulated radiation therapy in the advanced cancer

VernacularTitle:经皮胆管穿刺并调强适形放疗治疗晚期肿瘤阻塞性黄疸
Author: Changjie ZHOU
Publication Type:Journal Article
Keywords: Biliary puncture; Intensity modulated radiation therapy; Cancer; Obstructive jaundice
From: Cancer Research and Clinic 2013;(3):173-174,180
CountryChina
Language:Chinese
Abstract: Objective To evaluate the efficacy of advanced cancer treatment of obstructive jaundice by percutaneous biliary puncture and intensity modulated radiation therapy.Methods Nineteen patients with advanced cancer of obstructive jaundice were treated by skin biliary puncture combined with intensity modulated radiation therapy.Results In 19 patients evaluated by the WHO criteria,2 cases (10.5 ％) had complete response (CR),15 cases (78.9 ％) had partial response (PR),while 1 case (5.3 ％) had stable disease (SD) and 1 case (5.3 ％) got progressive disease (PD).Jaundice relieve rate was 94.7 ％ (18/19),6,8,12 months survival rates were 78.9 ％ (15/19),47.4 ％ (9/19),15.8 ％ (3/19),and the median overall survival time was 10 months.Conclusion Percutaneous biliary puncture combined with intensity modulated radiation therapy is well effective for patients with advanced cancer of obstructive jaundice,related toxicities are tolerable.These results indicate that further clinical study is of great worth.