Effect of L-NAME on apoptosis in the gerbil hippocampus after recirculation following ischemia
- VernacularTitle:左旋硝基精氨酸甲酯对脑缺血再灌注后海马区细胞凋亡的影响
- Author:
Jingjun ZHANG
;
Qing CHEN
;
Mingfeng YANG
- Publication Type:Journal Article
- Keywords:
cerebral ischemia;
hippocampus;
apoptosis
- From:
Chinese Pharmaceutical Journal
1999;(3):161-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE：To observe effect of L-NAME on apoptosis in the gerbil hippocampus after recirculation following ischemia.METHOD：Bilateral occlusion of common carotid arteries and TUNEL stain methods in gerbitil hippocampal tissue slice were used.RESULTS：L-NAME inhibited apoptosis in the CA1 subfield.CONCLUSION:Endogenous NO mediated apoptosis is inhibited by the L-NAME.
