Effects of Gushikangfuwan on osteoporosis induced by retinoic acid in rats
- VernacularTitle:骨蚀康复丸对维甲酸引起的大鼠骨质疏松的影响
- Author:
Shuling WANG
;
Jingli SUN
;
Taohua DUAN
- Publication Type:Journal Article
- Keywords:
Gushikangfuwan;
retinoic acid;
osteoperosis
- From:
Chinese Pharmaceutical Journal
1999;(2):96-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE：To study the effects of Gushikangfuwan on osteoporosis caused by retinoic acid in rats. METHODS:The osteoporosis was induced by retinoic acid(70mg.kg-1,ig)daily in rats for two weeks. The pharmacologic effects of Gushikangfuvan was observed. RESULTS: Compared with the retinoic acid group Gushikangfuwan (6g.kg-1)enhanced the relative bone volume,average bone trabecula and bone Lacuna length in rats.Gushikangfuwan (3g.kg-1,6g.kg-1) also enhanced the content of calcium and phosphorus of thigh bone. CONCLUSIONS：Gushikangfuwan may ameliorate the bone quality and enhance the bone density in rats.
