Study on BET in sodium bicarbonate injection with TAL
- VernacularTitle:鲎试剂用于细菌内毒素检测碳酸氢钠注射液的研究
- Author:
Xiaomeng ZHAO
;
Jiejiao YANG
;
Yongquan ZHU
- Publication Type:Journal Article
- Keywords:
sodium bicarbonate injection;
inhibition/strengthen test;
bacterial endotoxins test;
pyrogen test
- From:
Chinese Pharmaceutical Journal
1999;(2):116-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To determine whether bacterial endotoxins test(BET) can replace the pyrogen test for the sodium bicarbonate injection.METHODS:The comparative experiment of tachypleus amebocyte lysate(TAL) and rabbits were studied to determine the sensitivity.RESULTS:The sensitivity of TAL test was 0.125 EU.ml－1, 12 times higher than that of using rabbits.CONCLUSIONS:BET may replace pyrogen test.
