Diagnostic value of head-up tilt test with sublingual isosorbide dinitrate in patients with vasovagal syncope
10.3969/j.issn.1008-0074.2013.01
- VernacularTitle:倾斜试验合并舌下含化硝酸异山梨酯对血管迷走性晕厥的诊断价值
- Author:
Shunyin WANG
;
Junjie LIANG
;
Qingqi ZHANG
;
Yan LIU
- Publication Type:Journal Article
- Keywords:
Syncope, vasovagal;
Isosorbide dinitrate;
Tilt-table test
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2013;22(1):83-87
- CountryChina
- Language:English
-
Abstract:
Objective: To explore the diagnostic value of head-up tilt test with sublingual isosorbide dinitrate （HUTSI）in patients with vasovagal syncope (VVS). Methods: A total of fifty-two consecutive patients with clinically vasovagal syncope (VVS group) and thirty-eight control subjects without prior experience of syncope (normal control group) were evaluated by baseline head-up tilt table test (BHUT) , then the BHUT negative subjects underwent HUTSI test. . Results: (1) Positive BHUT test rate of VVS group and normal control group were 25% (13/52) and 0 respectively; from supine to HUT positive, there were significant decrease in heart rate [(73.1±8.5) times/min vs. (56.2±11.2) times/min] and mean arterial pressure [MAP, (81.2± 10.8) mmHg vs. (50.2±10.4) mmHg，P<0.05 both] in BHUT positive subjects. There were 21 HUTSI positive cases（53.9%）among the other 39 VVS patients, and two cases（5.3%）among the 38 subjects of normal control group. From supine to HUTSI positive, there were significant decrease in heart rate [(65.2±7.5) times/min vs. (52.9±10.5) times/min] and MAP [(78.3±10.7) mmHg vs. (48.8±11.2) mmHg, P<0.05 both] in HUTSI positive subjects. Duration from tilt started to positive reaction occurred in HUTSI positive group was significantly shorter than that of BHUT positive group [(10.8±9.3) min vs. (21.1±11.5) min，P<0.05]. All subjects can tolerate the test and only two cases in VVS group and one case in normal control group occurred headache and face red. Conclusion: Head-up tilt test with sublingual isosorbide dinitrate is a practical and easy-to- perform method with high sensitivity, specificity and few side effects for diagnosis of vasovagal syncope.
- Full text:W020130514542509529018.doc
