The effects of desflurane and sevoflurane on the intraocular pressure associated with endotracheal intubation in pediatric ophthalmic surgery.
10.4097/kjae.2013.64.2.117
- Author:
Jong Taek PARK
1
;
Hyun Kyo LIM
;
Kyu Yong JANG
;
Dea Ja UM
Author Information
1. Department of Anesthesiology and Pain Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea. umdj@yonsei.ac.kr
- Publication Type:Original Article ; Randomized Controlled Trial
- Keywords:
Desflurane;
Intraocular pressure;
Sevoflurane
- MeSH:
Anesthesia;
Anesthetics;
Arterial Pressure;
Entropion;
Heart Rate;
Hemodynamics;
Humans;
Intraocular Pressure;
Intubation;
Intubation, Intratracheal;
Isoflurane;
Methyl Ethers;
Reference Values;
Strabismus;
Stroke
- From:Korean Journal of Anesthesiology
2013;64(2):117-121
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: For ophthalmic surgery anesthesia, it is vital that intraocular pressure (IOP) is controlled. Most anesthetic drugs affect IOP dose-dependently, and inhalational anesthetics dose-dependently decrease IOP. In this study, we compared the effects of desflurane and sevoflurane on IOP and hemodynamics in pediatric ophthalmic surgery. METHODS: Thirty eight pediatric patients from the age of 6 to 15 years, who were scheduled for strabismus surgery and entropion surgery, were randomized to be administered desflurane (group D, n = 19) or sevoflurane (group S, n = 19). IOPs and hemodynamic parameters were measured before induction of anesthesia (B), after induction but immediately before intubation (AI), 1 min after intubation (T1), 3 min after intubation (T3), and 5 min after intubation (T5). RESULTS: The mean arterial pressure (MAP) at T1 and heart rates (HRs) at T1 and T3 were significantly higher in group D than those in group S. There was no significant difference between the groups in IOP, cardiac index (CI) and stroke index (SI). There was a significant difference within the group in IOP, SI, MAP and HR. There was no significant difference within the group in CI. CONCLUSIONS: There was no significant difference between the groups in IOP and hemodynamic parameters. The two anesthetic agents maintained IOP and hemodynamic parameters in the normal range during anesthetic induction.
