Scientific management of animal models of human diseases
10.3760/cma.j.issn.1006-1924.2012.02.019
- VernacularTitle:人类疾病模型动物的管理要点
- Author:
Shupei ZHOU
;
Zhenghui ZHENG
;
Guang JIA
- Publication Type:Journal Article
- Keywords:
Animal model of human disease;
Gene modified animal models;
Scientificmanagement
- From:
Chinese Journal of Medical Science Research Management
2012;25(2):129-130,146
- CountryChina
- Language:Chinese
-
Abstract:
In recent years,many kinds of animal models of human diseases with different genetic background were developed.Some were established in China,others were imported from abroad.Precious were these animal models,their biological features could be lost for various reasons,for instance,reverse from mutation,lost of modified or constructed gene,etc.This study provided some suggestions for scientific management of the animal models to in terms of quarantine inspection,specific feeding method and methods to maintain gene stability,so as to preserve their biological features.
