The long-term effects and influence factors analysis of arterial polyvinyl alcohol resin embolization in the treatment of non-small cell lung cancer

VernacularTitle:聚乙烯醇颗粒介入栓塞治疗非小细胞肺癌的远期疗效及影响因素分析
Author: Jun CAO ; Hongqiang LIU ; Yang HE ; Ning XIA ; Honglei ZHANG
Publication Type:Journal Article
Keywords: Polyvinyl alcohol resin; Cancer,non-small cell lung; Embolization
From: Chinese Journal of Primary Medicine and Pharmacy 2012;19(17):2561-2562,后插1
CountryChina
Language:Chinese
Abstract: Objective To investigate the long-term effects and risk factors of arterial polyvinyl alcohol resin (PVA) embolization for ⅢB and IV non-small cell lung cancer(NSCLC) patient.Methods 126 patients with 1 B or V NSCLC were performed the perfusion with 5-FU,THP,DDP by PVA grain embolization under fluoroscopic control.All patients were followed up.Kaplan-Meier was used to calculate the survival rate and the median survival time,and Cox regression model was adopted to analyze related risk factors which affected curative effect.Results The median survival time was( 11.78 ± 3.24) months and 1 -,2-year survival rate was 39.1 ％,25.59％ in 126 patients with NSCLC.Cox model analysis showed that of the tumor staging,tumor size,location and combination chemotherapy were all independent risk factors of prognosis (all P ＜ 0.01 ).Conclusion Arterial embolization of PVA for treatment of NSCLC is effective.Tumor size,stage,location and combination chemotherapy are associated with prognosis of NSCLC.