Simulation of axonal excitability using LABVIEW
10.3760/cma.j.issn.1673-4181.2012.02.008
- VernacularTitle:基于LABVIEW的轴突兴奋性仿真
- Author:
Zhen WANG
;
Qingli QIAO
;
Hongwei GUO
;
Fang LUO
- Publication Type:Journal Article
- Keywords:
Axon;
Action potential;
Ion channel;
LABVIEW;
Graphical programming
- From:
International Journal of Biomedical Engineering
2012;35(2):-
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveIn this paper a new application of LABVIEW in neural electrophysiological simulation was applied to simulate axonal excitability.MethodsA variety of axonal excitability of the squid giant axon was modeled with LABVIEW,including action potential threshold,refractoriness,temporal summation,anode break excitation,repetitive firing and conduction velocity.ResultsThe LABVIEW program accurately described the permeability changes of Na+ and K+ and their effects on the action potential,and the membrane excitability had been well predicted.ConclusionThe graphical programming language of LABVIEW allows the user to complete the programming by dragging and dropping icons and connecting wires,the users can quickly and easily construct their own biological research systems.