Endobronchial ultrasound-guided transbronchial needle aspiration for the diagnosis of thoracic sarcoidosis
10.3760/cma.j.issn.1001-4497.2011.09.006
- VernacularTitle:应用支气管内超声引导针吸活检术诊断胸部结节病
- Author:
Hui ZHAO
;
Jun WANG
;
Zuli ZHOU
;
Yun LI
;
Desong YANG
;
Xizhao SUI
;
Kezhong CHEN
;
Xiao LI
;
Jianfeng LI
;
Guanchao JIANG
;
Jun LIU
- Publication Type:Journal Article
- Keywords:
Sarcoidosis Diagnosis Biopsy;
needle Ultrasonography;
interventional
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2011;27(9):529-531,538
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluated the role of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in the diagnosis of thoracic sarcoidosis.Methods The study was retrospective,from September 2009 to June 2011,35 patients with suspected sarcoidosis,with enlarged hilar or mediastinal lymph nodes on computed tomography ( ≥1.0 cm),underwent EBUS-TBNA.Patients in whom EBUS-TBNA was nondiagnostic subsequently underwent surgical biopsy or a minimum of 6 months clinical and radiologic follow-up.Results EBUS-TBNA was performed on a total of 87 lymph node stations in 35 patients.Of the enlarged lymph nodes,64 (73.6％) were located in the mediastinal region and the remaining 23 ( 26.4％ ) around the hilar or interlobar area.A final diagnosis of sarcoidosis was made for 28 (80％) of the patients.In patients with a final diagnosis of sarcoidosis,EBUS-TBNA demonstrated noncaseating epithelioid cell granulomas in 25 ( 89.3％ ) of the patients.EBUS was well tolerated by all of the patients with no complications.Conclusion EBUS-TBNA is a safe procedure with a high yield for the diagnoses of thoracic sarcoidosis of stage Ⅰ or Ⅱ.
