Predictive value of amino-terminal pro-B-type natriuretic peptide on short term prognosis in patients with acute coronary syndrome
10.3969/j.issn.1008-0074.2012.04.03
- VernacularTitle:血浆N末端B型利钠肽原对急性冠脉综合征患者近期预后的预测价值
- Author:
Kaili YAN
;
Xiaojun HU
;
Su CHEN
;
Yueling SUN
;
Hanhua LIU
;
Lifen GUO
;
Yuanchao TU
- Publication Type:Journal Article
- Keywords:
Natriuretic peptide, brain;
Coronary artery disease;
Prognosis
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2012;21(4):349-353
- CountryChina
- Language:English
-
Abstract:
Objective: To evaluate the predictive value of plasma amino-terminal pro-B-type natriuretic peptide (NT-proBNP) on short term prognosis in patients with acute coronary syndrome (ACS). Methods: Plasma NT-proBNP levels were measured in ACS patients within 24 h after admission with ELISA method. The 600 ACS patients were divided into two groups: event group （n=108）and no-event group （n=492）according to occurrence of cardiovascular events（including cardiac death, cardiac shock and heart failure）, The NT-proBNP levels were compared between two groups. Single factor and multiple factor Logistic regression analyses were used to evaluate if NT-proBNP was an independent predictor for short term prognosis. Results: The plasma NT-proBNP levels of event group were significantly higher than those of no-event group [1361.2 (965.3, 2088.6) pmol/L vs.605.7 (274.5, 1177.8) pmol/L, p<0.01]. Multiple factor Logistic regression analyses demonstrated that plasma NT-proBNP was an independent predictor for short term prognosis (OR=1.000, p<0.01) in ACS patients. Conclusion: Plasma NT-proBNP was an independent predictor for short term prognosis in ACS patients.
- Full text:P020121009769541569189.doc
