Triage of women with atypical squamous cells of undetermined significance cytology result

VernacularTitle:宫颈细胞学不明确意义不典型鳞状细胞结果的分流处理
Author: Lei PAN ; Dafeng YE
Publication Type:Journal Article
Keywords: Uterine cervical dysplasia; Cytology; Papillomatirus infections; Biological markers
From: Journal of International Oncology 2011;38(3):230-232,240
CountryChina
Language:Chinese
Abstract: Repeat cervical cytologic testing,human papillomavirus(HPV)testing and immediate colposcopy are currently the most general managements in women with atypical squamous cells of undetermined significance(ASCUS)result.However,the efficacy of these three methods is hampered by strong subjectivity,high false negative and positive rates.With the development of the aetiology of cervical cancer,there is good evidence that biomarkers for persistent HPV infection,HPV integration,instability of host genes and malignancy triage ASCUS more objectively and efficiently.The three-dimensional multiparameter biomarker-based detection may be the predominant method for the triage of women with abnormal cervical cancer screening result.